Poplar Bluff Regional Medical Center is located in the heart of Southeast Missouri. Poplar Bluff, the hometown of Poplar Bluff Regional Medical Center, is a rural community with a population of approximately 17,000. Poplar Bluff Regional Medical Center is the community's largest employer, with more than 1,400 employees.
Surrounded by many smaller rural towns, many residents of other communities travel to Poplar Bluff for jobs, healthcare, shopping and dining. Poplar Bluff Regional Medical Center also serves these communities not only through our hospital services, but with our Outreach Services Family Clinics.